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An I.M. injection is given ____.

  1. In the mouth

  2. In the vein

  3. In the muscle

  4. In the joint

The correct answer is: In the muscle

An intramuscular (I.M.) injection is a type of injection that is given directly into a muscle. This is different from an intravenous (IV) injection, which is given into a vein (B) or an intra-articular injection, which is given into a joint (D). An I.M. injection should not be given in the mouth (A) as it can lead to infections and complications. Therefore, the correct option is C, in the muscle.